Methotrexate appears to take longer to start acting, but is no less effective than the corticosteroid prednisone as a first-line treatment for pulmonary sarcoidosis, according to the early findings of an ongoing Phase 4 clinical trial. The researchers noted that, while methotrexate treatment is associated with a similar number…
The Foundation for Sarcoidosis Research (FSR) is partnering with Walgreens and Cedars-Sinai to provide free N95 face masks at two locations in Los Angeles, with the goal of helping members of the community protect their lungs following January’s wildfires. Exposure to fine particulate matter from soot and ash in…
April is Sarcoidosis Awareness Month, and this year’s theme, as chosen by the Foundation for Sarcoidosis Research (FSR), is “Facing Sarcoidosis Together” — which seeks to recognize the unique ways in which community, support, and advocacy can help patients navigate their disease. “Living with sarcoidosis presents significant challenges,…
Enrollment is complete in the dose-finding phase of a Phase 1b/2b clinical trial evaluating Xentria’s investigational therapy XTMAB-16 in adults with pulmonary sarcoidosis, and screening for the next phase is expected to start next fall. The Phase 1b/2 study (NCT05890729) enrolled 39 pulmonary sarcoidosis patients in four…
Cutaneous sarcoidosis patients with lesions on the head and face are significantly more likely to also have cardiac sarcoidosis, which is when the disease reaches the heart, a small study in the U.S. suggests. The findings indicate the distribution of skin lesions is linked to the risk of…
Nearly 350 people joined a virtual public meeting that the Foundation for Sarcoidosis Research (FSR) ran as part of a U.S. Food and Drug Administration (FDA) program to discuss the unmet needs and challenges faced by those living with sarcoidosis. In the Externally Led Patient-Focused Drug Development meeting,…
Nonsteroidal immunosuppressants may be a treatment option for people with cardiac sarcoidosis who don’t respond well to corticosteroids or have side effects from using them, a Japanese study suggests. While nonsteroidal immunosuppressants reduced the need for corticosteroids and how active sarcoidosis lesions were for some patients, more research is…
A 30-year-old man with renal cell carcinoma — a type of kidney cancer — developed sarcoid-like reactions in his spleen, liver, and lungs, which went away after the tumor’s removal, suggesting that such reactions arose from an unusual immune response against the tumor. The man’s case was described in a…
The Foundation for Sarcoidosis Research (FSR) has awarded $100,000 in funding to support U.S.-based research projects aimed at improving knowledge and diagnosis of cardiac sarcoidosis, a type of sarcoidosis that affects the heart. The funds were split into two cardiac sarcoidosis-specific grants, of $50,000 each. One…
The prognosis for people with cardiac sarcoidosis may depend on the condition of their heart at diagnosis and not on whether other organs are also affected, a study in Japan suggests. Isolated cardiac sarcoidosis, where the disease is limited to the heart, is a significant risk factor for worse…
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