News

Ear, nose, and throat (ENT) conditions may be underdiagnosed among adults with sarcoidosis, a large U.S. database study suggests. Research showed that sarcoidosis patients had more than 45% higher odds of having recorded diagnoses of sinus, swallowing, voice, and cranial nerve-related conditions than their matched peers without sarcoidosis. The…

The Foundation for Sarcoidosis Research (FSR) has selected more than a dozen clinical centers to serve as inaugural sites for its newly launched U.S.-based registry that aims to enroll at least 2,000 people with sarcoidosis. The FSR Clinical Data Registry will help support high-quality, standardized clinical data…

The Foundation for Sarcoidosis Research (FSR) is teaming up with the Patient Advocate Foundation to offer a new support program for people with sarcoidosis who need help navigating insurance, disability benefits, and other financial challenges. “For far too long, patients living with sarcoidosis have had to navigate…

People with pulmonary sarcoidosis who undergo a lung transplant face greater short-term risks after surgery but have better long-term survival compared with individuals undergoing the procedure due to other lung conditions. Those are the key findings of a large U.S. study that investigated outcomes among people for whom the…

Nearly 4 in 10 people with pulmonary sarcoidosis had a relapse after reducing or stopping treatment, according to a review of more than 50 published studies. Most studies with timing data reported relapses occurring within 1.5 years of reducing or discontinuing treatment. Black patients and those with more advanced…

The Ann Theodore Foundation (ATF) and the Milken Institute have awarded $600,000 to three early-career researchers studying sarcoidosis in the U.S., with the goal of improving understanding of the disease, as well as its treatment and care. The new grant program, called Ann Theodore Foundation Learning Opportunities…

The antimalarial medication hydroxychloroquine may help treat uveitis, a type of eye inflammation, in some people with ocular sarcoidosis, a study reports. Specifically, over half of the 42 people with sarcoidosis-related uveitis (SAU) responded to hydroxychloroquine, sold under the brand names Plaquenil and Sovuna, with generics available. This allowed…

In cutaneous sarcoidosis, disease-driving immune cells ramp up their energy production, and blocking this energy production may be a useful strategy for treating the disease, a new study shows. The study specifically points to metformin, a metabolism-modulating drug that’s widely used to treat diabetes, as a potential treatment for…

Levels of specific immune complement proteins in blood and cerebrospinal fluid, including C3, factor B, and C5, showed strong potential for distinguishing people with neurosarcoidosis from those without the disease, according to a small study in the U.K. Combinations of several complement proteins yielded more discriminative potential, while combining…

A common genetic variant in the TNFR1 gene, which encodes a protein involved in regulating inflammation, may help identify people with sarcoidosis who are at higher risk of worsening lung function, a new study suggests. Researchers found that patients carrying two copies of the more common form of the…