Kinevant Sciences’ experimental therapy namilumab failed to show a benefit for people with chronic, active pulmonary sarcoidosis in a Phase 2 clinical trial involving more than 100 patients. Based on the negative results of the RESOLVE-Lung study (NCT05314517), the company announced it will be discontinuing further development…
People with sarcoidosis in the U.S. are more likely than those in the general population to have certain co-occurring autoimmune disorders, including lupus and multiple sclerosis (MS). That’s according to “Autoimmune comorbidities associated with sarcoidosis: a case-control study in the All of Us research program,” which…
The lungs are affected in nearly everyone diagnosed with sarcoidosis in the Netherlands, but most patients in the country don’t have disease severe enough to warrant systemic immune-suppressing treatments at the time of diagnosis. That’s according to the findings of a new study, “Organ involvement in…
Treatment with Remicade (infliximab) is generally effective for controlling sarcoidosis when it affects the nervous system or liver, but patients whose disease affects the skin or skeletal system aren’t as likely to respond to it, a study reports. “[Remicade] shows promise for treating patients with sarcoidosis, particularly with…
A test that detects disease-specific antibodies in the blood could help to diagnose sarcoidosis more quickly and easily, according to a recent study. “More testing needs to be completed before this screening method is ready for clinical use, but it’s possible that could be a reality within a few…
Acthar Gel (repository corticotropin injection) treats African Americans with sarcoidosis as effectively as it does patients of other races, a study suggests. The study, “Acthar Gel in African Americans versus Non-African Americans with Symptomatic Sarcoidosis: Physician Assessment of Patient Medical Records,” was published in Therapeutics…
Scientists at the University of Colorado are planning a study to better classify sarcoidosis as it affects the eyes, called ocular sarcoidosis. Having a grasp on the specific biological mechanisms that drive sarcoidosis in different patients could lead to more targeted treatments, researchers say. “Improving our ability to define…
Having elevated levels of a protein called BNP is associated with an increased risk of death and serious heart health problems in people with cardiac sarcoidosis, a study has found. Results also suggest inflammation of the heart muscle (myocardium) or reduced function of the left ventricle (the part of…
Researchers in Austria and the U.K. have created the first mouse model that mimics the human disease of cardiac sarcoidosis. “To our best knowledge this is the first animal model of cardiac sarcoidosis that recapitulates major … hallmarks of human disease,” scientists wrote, adding that it is expected to…
The Ann Theodore Foundation and the Milken Institute are once again teaming up to offer grants worth up to $3.4 million to help spur research into sarcoidosis. “Varied perspectives and expertise are key to achieving progress in sarcoidosis research, which will then lead to better treatment,” Lisa…
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