Treatment with Rituxan (rituximab) provided marked disease remission and was well-tolerated by three patients with refractory neurosarcoidosis, according to a new case report. The study, “Successful therapy with rituximab in three patients with probable neurosarcoidosis,” was published in the journal Therapeutic Advances in Neurological…
Adalimumab — marketed by (Abbvie) as Humira — can help treat patients with verrucous sarcoidosis — a rare type of cutaneous (skin) sarcoidosis — associated with human papillomavirus (HPV) infection, according to a new case report. The study, “Chronic verrucous sarcoidosis associated with human papillomavirus infection:…
With the U.S. midterm elections now less than two weeks away, patient advocacy groups are solidly focused on a range of hot-button issues, from the Orphan Drug Tax Creditand affordable health insurance to future funding for rare disease research. Yet “whether Democrats take over the House or Senate, or…
Cardiac arrhythmias are increasing among sarcoidosis patients, and they are linked with higher hospital admission and mortality rates, a U.S. patient population study finds. These results, published in the study, “The burden of cardiac arrhythmias in sarcoidosis: a population-based inpatient analysis,” highlight the need for timely diagnosis…
Highly sensitive magnetic resonance imaging (MRI) of the spinal cord shows that spine involvement is prevalent in sarcoidosis patients, mostly affecting the cervical region, a detailed re-analysis of imaging data reports. The study, “Imaging findings in spinal sarcoidosis: a report of 18 cases and review…
The presence of certain types of bacteria, specifically gram-negative bacteria other than Pseudomonas aeruginosa, increases the risk of death, admission to an intensive care unit (ICU), and the need for vasopressors in patients with sarcoidosis or other interstitial lung diseases (ILD) who are hospitalized, a study…
Half a year has gone by since disgraced pharma executive Martin Shkreli was sentenced to seven years in federal prison for securities and wire fraud while heading San Diego-based Retrophin. As founder and CEO of another company (then known as Turing Pharmaceuticals), in late 2015 Shkreli bought the rights…
A 49-year-old woman in Australia was simultaneously diagnosed with a rare case of cutaneous sarcoidosis and recurrent metastatic breast cancer, according to a case report. The study “Concurrent diagnoses of cutaneous sarcoidosis and recurrent metastatic breast cancer: more than a coincidental occurrence?” was published in the journal…
aTyr Pharma, which developing therapies to modulate immune pathways involved in lung diseases, has announced an upcoming Phase 1b/2a study to test their lead therapy ATYR1923 in patients with pulmonary sarcoidosis. ATYR1923 is an immunomodulatory molecule that’s able to bind to the Neuropilin-2 (NRP-2) receptor protein, part of…
Patients with sarcoidosis are more likely to have heart rhythm disorders, specifically ventricular tachycardia, and experience cardiac arrest, a review of a large sample of inpatients in the United States found. Greater rates of heart complications in sarcoidosis patients may…
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