Sarcoidosis is a rare and chronic inflammatory condition, in which clumps of immune cells called granulomas build in one or more organs. These granulomas can prevent organs from working as they should, and may cause permanent damage. The lungs are most commonly affected organ, with some 90 percent…
Search results for:
Sarcoidosis is caused by chronic and systemic inflammation resulting in the accumulation of small clumps of immune cells called granulomas in several organs. Diagnosing the disease can be challenging because sarcoidosis’Â symptoms vary greatly. Early symptoms are also shared with a number of other disorders, and a diagnostic test…
The National Heart, Lung, and Blood Institute, part of the National Institutes of Health (NIH), has given a $1.98 million grant to Wayne State University researchers to refine an antibody-based technology that can help to distinguish people with  sarcoidosis from tuberculosis patients and healthy individuals. Sarcoidosis is an…
Researchers from Karolinska Institutet in Sweden, reported finding eight proteins in bronchoalveolar fluid (lung washing liquid) in the largest group of patients with sarcoidosis to be studied that distinguishes people with the disease from healthy people and those with asthma. The findings presented in the report “Elevated levels of…
A case was recently reported of a 27-year-old woman who presented ocular pain and moderate vision impairment as the first symptoms of sarcoidosis. Clinicians from the University of Ottawa in Canada reported the case study in the Canadian Medical Association Journal. Sarcoidosis is an inflammatory chronic disease that can…
Genes that have been linked to the likelihood of developing sarcoidosis may not necessarily be associated with disease course, according to a study conducted in Portugal, which also points to other genes that may help to predict a patient’s outcome. The study, “Associations Between Sarcoidosis Clinical Course And ANXA11 Rs1049550 C/T, BTNL2 Rs2076530 G/A,…
An immune cell called a type 1 innate lymphoid cell is found at much higher levels in skin granulomas, that is, clumps of immune cells, of people with sarcoidosis relative to those with non-sarcoid skin granulomas, according to research that shows high levels of the cells were also found…
Use of high-resolution computed tomography (HRCT) imaging technique can help identify features of thoracic sarcoidosis, researchers in India report. Because of its superior imaging capacity, they said, this method may allow clinicians to identify subtle chest abnormalities commonly undetectable by standard methods. The results were published in the study “…
“Don’t let the day get away from you!” Growing up, I remember my family members saying this to my brother and me regularly. It means that you shouldn’t let the day pass you by without doing something. That something could be anything, as long as it was constructive. It was…
A global Phase 3 clinical trial evaluating efzofitimod, Atyr Pharma’s investigational therapy, in people with pulmonary sarcoidosis will continue as planned following a third pre-planned interim safety review. An independent data safety and monitoring board (DSMB) examined available safety and tolerability data from all 268 participants enrolled in…