Sarcoidosis can present several distinct clinical manifestations, and some of these can mimic other diseases. Therefore, it is essential for clinicians to have as much complete and detailed information as possible to allow for an accurate diagnosis. Skin manifestations can be the first symptom of sarcoidosis. But sarcoidosis and chronic cutaneous lupus…
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Sarcoidosis should be considered as a differential diagnosis in case of nail lesions, according to a study published in the journal Skin Appendage Disorders, where researchers from São Paulo in Brazil report the case of two patients. This would allow an early diagnosis of systemic sarcoidosis.
Cryptococcal meningitis, a rare but life-threatening complication of sarcoidosis, is often misdiagnosed as neurosarcoidosis, delaying proper treatment and reducing a patient’s chances of complete recovery, researchers report. Investigators behind the study, “Cryptococcal meningitis complicating sarcoidosis,” published in the journal Medicine, suggest that physicians test for CSF…
A new study suggests that sarcoidosis patients have different expression levels of certain RNA-binding proteins (RBPs) compared to healthy individuals, and that this difference is associated with the development of the disease. The study, “Expression Profile of Six RNA-Binding Proteins in Pulmonary Sarcoidosis,” was published in the journal…
Autoimmune Hemolytic Anemia in Sarcoidosis Patient Successfully Treated with Rituxan, CellCept Combo
Patients with sarcoidosis may develop a condition known as autoimmune hemolytic anemia, in which the red blood cells are prematurely destroyed by the immune system. Although this is not well documented, researchers at Warwick Hospital in England have reported the case of a patient who exhibited both illnesses. Their study,…
There is a difference in the composition of microorganisms in the respiratory tract of people with sarcoidosis and that of healthy individuals according to a study conducted by Polish scientists. The authors of the study suggest that this may be a factor contributing to an increased colonization of the airways by opportunistic pathogenic bacteria.
Poor cardiac outcomes in patients with cardiac sarcoidosis may be predicted through the presence of cardiac fibrosis assessed by heart magnetic resonance imaging (MRI), according to a recent Japanese study. The study, “Risk stratification for major adverse cardiac events and ventricular tachyarrhythmias by cardiac MRI in patients with…
The results of a clinical study conducted over 20 years in a group of patients seen and treated at three large teaching hospitals in London shows that patients with sarcoidosis who experience an inflammatory optic neuropathy, or damage to the optic nerve due to inflammation, respond to treatment with corticosteroids.
Researchers at the National Research Institute of TB & Lung Diseases, in Poland, have developed a novel tool that helps identify patients with cardiac sarcoidosis via easily accessible and cost-effective tests. The study “Prevalence of cardiac sarcoidosis in white population: a case–control study: Proposal for a novel risk…
It is important to perform a lung biopsy when a change in chest X-ray is seen during pulmonary sarcoidosis monitoring, according to research conducted by Japanese scientists. This way, the rare possibility of complication with multicentric Castleman’s disease (MCD) can be ruled out or in the rare case it is diagnosed, appropriate treatment can be given to the patient.