aTyr Pharma has announced a collaboration with The Ohio State University (OSU) to conduct cell culture studies seeking to identify potential biomarkers that can predict ATYR1923’s therapeutic effectiveness in people with pulmonary sarcoidosis. The research, which extends previous proof-of-concept findings, will delineate the pathways involved in sarcoid granuloma formation…
Search results for:
Careful evaluation is required to distinguish among sarcoidosis, silicosis, and silicosarcoidosis, three disorders that can cause similar patterns of lung problems in people exposed to silica, but that progress and respond to treatment differently. A team of scientists in Brazil highlighted the challenges of distinguishing among the three conditions…
Columns
The Heroes of the Pandemic Era
On April 28 of last year, I had one thing on my mind and it wasn’t my sarcoidosis. I was crammed in a movie theater for “Avengers: Endgame” learning the fate of my favorite superheroes. Filling theaters in record-breaking numbers may now be a thing of the past. But, what…
Sarcoidosis is a rare inflammatory disease that can affect any part of the body. It is characterized by an overactive immune system that leads to the build-up of clusters of immune cells, called granulomas in different organs and tissues. These granulomas can prevent the normal function of organs and…
As a Marvel fan, this week’s long-awaited premiere of “Avengers: Endgame” has me thinking about the sarcoidosis community’s hidden superpowers. They aren’t flashy. We can’t fly. We can’t shoot webs from our wrists and swing through neighborhoods. And we can’t transform our bodies into a hulking green beast — though…
Pentoxifylline is a treatment that has been approved by the U.S. Food and Drug Administration to improve blood flow. It can also be used to treat sarcoidosis. How pentoxifylline works In addition to improving blood flow, pentoxifylline inhibits the synthesis of a pro-inflammatory, or immune-activating factor, called…
Recently, I thought about my past hospitalizations and how isolated I felt. I guess the events over the past three months with social distancing had me feeling isolated … again. I thought about the two months I spent in the lung center at one of our hospitals in…
More than 90 percent of people with sarcoidosis have lung involvement, which makes it hard for me not to worry about the recent coronavirus outbreak. Last week, the World Health Organization declared the coronavirus that causes COVID-19 a global pandemic. We are being bombarded daily with…
I took a shower yesterday and then had a hard look at myself in the mirror. I didn’t like everything I saw. Later, I was helping my wife clean our living room and I saw a photo of my dad I had taken years ago. I didn’t like what I…