Magdalena Kegel,  —

Obesity is linked to an increased risk of sarcoidosis, while smoking was associated with a lower risk, according to a study reviewing medical records of nearly 350 patients. Although the study, “Smoking, obesity and risk of sarcoidosis: A population-based nested case-control study,” published in the journal…

A case study of a woman, with both breast cancer and sarcoidosis in her breast lymph nodes, highlights the difficulties in distinguishing between these two conditions. The report, “Sarcoidosis imitating breast cancer metastasis: a case report and literature review,” published in the journal Cancer Biology & Medicine, also again calls attention to an apparent…

Researchers recently linked pulmonary sarcoidosis to a receptor activated during certain infections that may contribute to disease development via the release of an inflammatory factor in immune cells. The study, “Functional Toll-Like Receptor 9 Expression and CXCR3 Ligand Release in Pulmonary Sarcoidosis,” was published in the American Journal…

Endobronchial sarcoidosis can cause diffuse bronchiectasis, as demonstrated in a recently presented case report of a 50-year-old patient. To cover for the possibility that bronchiectasis was caused by endobronchial sarcoidosis, a research team suggested that a bronchoscopy and a tissue sample from inside a bronchus should be included in bronchiectasis…

Exposure to mold and bacteria could be a potential trigger of lung sarcoidosis, according to a study revealing that immune cells from the blood of sarcoidosis patients are more sensitive to such agents. The study, “Fungal cell wall agents and bacterial lipopolysaccharide in organic dust as possible risk…

Cryptococcal meningitis, a rare but life-threatening complication of sarcoidosis, is often misdiagnosed as neurosarcoidosis, delaying proper treatment and reducing a patient’s chances of complete recovery, researchers report. Investigators behind the study, “Cryptococcal meningitis complicating sarcoidosis,” published in the journal Medicine, suggest that physicians test for CSF…

Cancer immunotherapy with Opdivo (nivolumab) and Yervoy (ipilimumab) may or may not trigger sarcoidosis in rare cases, a report from Yale University School of Medicine shows. The study, “Immune-related sarcoidosis observed in combination ipilimumab and nivolumab therapy,” published in the Journal of the American Academy of…

Researchers at the University of Washington in Seattle identified numerous gene pathways that are altered in sarcoidosis, not only confirming the involvement of the innate immune system, but also demonstrating that systems for protein breakdown are activated in the disease. The study, “Sarcoidosis activates diverse transcriptional…

Researchers at Jichi Medical University in Japan reported a case of sarcoidosis relapse in a woman who developed renal dysfunction, high calcium levels, as well as kidney and urethral stones. The report, “Renal Failure Found during the Follow-up of Sarcoidosis: The Relevance of a Delay in…

Japanese researchers described a rare case study of neurosarcoidosis affecting only the central nervous system then concluded that while the condition is easy to treat, its diagnosis is difficult. The case report, “Isolated neurosarcoidosis presenting with multiple cranial nerve palsies,“ published in the journal Surgical…