Author Archives: Magdalena Kegel

PAH Drugs of Limited Benefit in Sarcoidosis-linked Pulmonary Hypertension, Study Finds

Treatment with medications for pulmonary arterial hypertension (PAH) do not significantly help people with sarcoidosis-associated pulmonary hypertension (PH), researchers from France’s University of Paris-Sud reported. Their study, “Management and long-term outcomes of sarcoidosis-associated pulmonary hypertension,” — published in the European Respiratory Journal — showed that while PAH-drugs improved some disease…

Study Supports Theory That Bacteria Causes Sarcoidosis, Researchers Say

Researchers found bacteria of the type Propionibacterium acnes in a large proportion of tissue samples from patients with cardiac sarcoidosis, suggesting that the bacteria may cause the formation of granulomas (abnormal collections of inflammatory cells), a typical feature of sarcoidosis. The work, published in the journal PLOS ONE, indicated that…

Study Details 3 Cancer Patients Who Developed Sarcoidosis After Dendritic Cell Vaccines

Sarcoidosis may appear in cancer patients who respond well to treatment with dendritic cell-based vaccines, according to a case series report from Germany. At the Friedrich-Alexander-University Erlangen-Nürnberg and the associated Erlangen University Hospital, researchers noted three patients with malignant melanoma who developed sarcoidosis after or during such treatment.

Abnormal Numbers of Certain T-Cells May Explain Melanoma-Sarcoidosis Link

Increased levels of a specific type of T-cell in some patients with melanoma might explain the connection between the cancer and sarcoidosis, researchers suggest in a study that explored melanoma patients treated with immunotherapy. The study, “Immunotherapy-induced sarcoidosis in patients with melanoma treated with PD-1 checkpoint inhibitors: Case series and…