Posts by: Patricia Inacio, PhD

Patricia Inacio, PhD

Patricia holds her Ph.D. in Cell Biology from University Nova de Lisboa, and has served as an author on several research projects and fellowships, as well as major grant applications for European Agencies. She also served as a PhD student research assistant in the Laboratory of Doctor David A. Fidock, Department of Microbiology & Immunology, Columbia University, New York.

June 4, 2020June 4, 2020

ATYR1923 Binds to NRP2 Protein Found at Key Immune Cells, Data Show

News

ATYR1923, a candidate therapy for pulmonary sarcoidosis, binds specifically to the neuropilin-2 (NRP2) receptor protein, which is located at the surface of immune cells responsible for inflammation and granuloma ... Read more

March 9, 2020March 9, 2020

Pediatric Rare Disease Therapies Increase, But Most Repurposed, Study Finds

News

The number of treatments for children with rare diseases has grown over the past decade, according to a new study. However, despite the increase, nearly 7,000 rare diseases are still ... Read more

February 24, 2020February 24, 2020

Imbalance in Certain Immune Cells May Promote Pulmonary Sarcoidosis, Study Suggests

News

Researchers have discovered that patients with pulmonary sarcoidosis have an imbalance in two subsets of immune cells, namely B-cells and follicular T-helper cells — findings that support the potential ... Read more

December 9, 2019December 9, 2019

Subgroup of Active T-cells Linked to Worse Disease in Sarcoidosis, Study Reports

News

The lungs of patients with sarcoidosis are burdened with a more active subset of immune T-cells, called mucosal-associated invariant T (MAIT) cells, a study reports. The activity of these ... Read more

September 30, 2019September 30, 2019

LAS System May Fail to Identify Sarcoidosis Patients at Urgent Need of Lung Transplant, Study Finds

News

The current scoring system used to assess the urgency of lung transplants, called LAS (lung allocation score), fails to predict the risk of death in people with sarcoidosis, a ... Read more

June 3, 2019June 3, 2019

Pulmonary Hypertension Therapies May Help Heart Conditions in Certain Sarcoidosis Patients, Study Suggests

News

While there no therapies approved for sarcoidosis-associated pulmonary hypertension (SAPH), pulmonary hypertension-specific therapies may help ease right heart dysfunction in a select group of patients, according to results of ... Read more

March 11, 2019March 11, 2019

Investigational Therapy ATYR1923 May Relieve Lung Inflammation, Preclinical Data Show

News

The investigational therapy ATYR1923 for pulmonary sarcoidosis may help decrease lung inflammation by halting the infiltration of immune cells called neutrophils into the lungs, according to a preclinical study ... Read more

February 18, 2019February 18, 2019

Familial Sarcoidosis Prevalent in Certain Populations Worldwide, Review Suggests

News

A literature review of research performed in specific populations from countries worldwide estimated a heritability of 60 to 70 percent for familial sarcoidosis, a study has found. The study ... Read more

January 7, 2019January 7, 2019

Impaired Lung Function Linked to Higher Risk of Dementia, Mild Cognitive Decline Later in Life

News

Middle-aged adults with impaired lung function, such as people with sarcoidosis, are at higher risk of dementia and mild cognitive impairment, according to a long-term follow-up study. The study, ... Read more

October 25, 2018October 25, 2018

Burden of Cardiac Arrhythmias Increasing in Sarcoidosis Patients, US Study Reports

News

Cardiac arrhythmias are increasing among sarcoidosis patients, and they are linked with higher hospital admission and mortality rates, a U.S. patient population study finds. These results, published in the ... Read more

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