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Cardiac troponin T may be cardiac sarcoidosis prognosis biomarker

Blood levels of high-sensitivity cardiac troponin T (hs-cTnT), a marker of heart muscle damage, may serve as a prognostic biomarker for adverse events, including death and heart failure, in people with cardiac sarcoidosis, a study in Japan shows. Patients with combined elevated levels of both hs-cTnT and B-type natriuretic…

Small-airway biopsy may help with diagnosing sarcoidosis: Study

More than one-third of sarcoidosis patients have abnormalities in the small airways, or bronchioles, according to a study in Italy that looked at small-airway inspection and biopsy using ultrathin tubes. The researchers said this procedure could aid in diagnosing sarcoidosis. Small-airway biopsies yielded high rates of granuloma detection: 65.4%…

Pulmonary sarcoidosis treatment efzofitimod Phase 3 trial to go on

A global Phase 3 clinical trial evaluating efzofitimod, Atyr Pharma’s investigational therapy, in people with pulmonary sarcoidosis will continue as planned following a third pre-planned interim safety review. An independent data safety and monitoring board (DSMB) examined available safety and tolerability data from all 268 participants enrolled in…

Elevated blood fat levels may increase risk of sarcoidosis: Study

Elevated blood levels of fatty molecules, or lipids — specifically triglycerides and low-density lipoprotein cholesterol (LDL-c), also known as bad cholesterol — may be linked with an increased risk of developing sarcoidosis, while certain lipid-lowering medications may help reduce the risk. That’s according to a study that looked at…