News

High blood calcium levels, or hypercalcemia, may in rare cases be a symptom of sarcoidosis, according to a case report from Morocco. Steroid medications helped ease the symptom for a man with severe hypercalcemia as a main complication of sarcoidosis of the lungs, or pulmonary sarcoidosis, according to…

A 30-year-old man with renal cell carcinoma — a type of kidney cancer — developed sarcoid-like reactions in his spleen, liver, and lungs, which went away after the tumor’s removal, suggesting that such reactions arose from an unusual immune response against the tumor. The man’s case was described in a…

Enrollment in aTyr Pharma’s pivotal Phase 3 EFZO-FIT clinical trial, testing the effectiveness and safety of efzofitimod in people with pulmonary sarcoidosis, is now complete. The study exceeded its target number of participants, recruiting 268 patients in 85 centers across the U.S., Europe, Japan, and Brazil. Top-line data are expected…

Being Black or having restrictive lung disease, where it’s hard to take in enough air in a breath, were factors that predicted faster lung function declines in people with pulmonary sarcoidosis in a recent U.S. study. “This study can inform future prospective studies to further explore pulmonary function phenotypes…

A woman who underwent a heart transplant for cardiac sarcoidosis later showed signs of sarcoidosis in the brain, a condition known as neurosarcoidosis, highlighting the need for better protocols to monitor and treat sarcoidosis patients after a transplant, scientists report. Immunosuppressive treatments helped to ease the woman’s neurological…

A new modeling approach that incorporates standard tests and clinical signs can identify people who have sarcoidosis-associated uveitis (SAU), or inflammation of the eye, a new study shows. Based on this analysis, data showed a combination of eye tests could distinguish SAU from non-SAU patients with a high degree…

Microblading, a cosmetic technique that employs fine needles to deposit pigment to mimic the appearance of hairs, may be among triggers for sarcoidosis, according to a study. “When esthetic procedures become increasingly popular, patients with chronic lesions at the injection site of the foreign material, especially macular, papular, or…

People with sarcoidosis in the U.S. are more likely than those in the general population to have certain co-occurring autoimmune disorders, including lupus and multiple sclerosis (MS). That’s according to “Autoimmune comorbidities associated with sarcoidosis: a case-control study in the All of Us research program,” which…

A 79-year-old  woman was diagnosed with spinal sarcoidosis based on the analysis of skin lesions from her scalp, according to a case study from Japan. Although a spinal MRI revealed the presence of spinal cord lesions, their cause was unknown. The presence of skin granulomas, observed in a scalp…

A 37-year-old woman in Japan developed a granuloma — the clumps of cells that characterize sarcoidosis — in her thyroid gland that spontaneously regressed without steroid treatment, a case study reports. The woman also showed lesions in the skin and salivary gland, suggesting “thyroid sarcoidosis should be considered in…