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Underdiagnosis of cardiac sarcoidosis leaves people at risk

Only about one in four patients with unexplained, life-threatening arrhythmias are tested for cardiac sarcoidosis, even though medical guidelines call for it, according to a large worldwide study. As a result, cardiac sarcoidosis remains largely underdiagnosed, a problem that “carries significant risks, including delayed treatment and the potential for…

Overactive immune genes may fuel sarcoidosis inflammation: Study

Sarcoidosis appears to involve activation of several immune pathways, particularly those guiding responses against some common viruses. These are the findings of a study that looked for immune signatures of the disease by analyzing differences in gene activity between people with sarcoidosis and healthy controls. “These findings support the…

Rituximab treatment may help some neurosarcoidosis patients

Treatment with rituximab can lead to meaningful improvements for some people with neurosarcoidosis affecting the brain and/or spinal cord — particularly those with hard-to-treat disease and involvement limited to some nerves. That’s according to a retrospective study of 19 people treated across four U.S. centers, which showed that…