A literature review of research performed in specific populations from countries worldwide estimated a heritability of 60 to 70 percent for familial sarcoidosis, a study has found. The study titled “Clinical epidemiology of familial sarcoidosis: A systematic literature review” was published in the journal Respiratory Medicine. While the…

A case study diagnosing sarcoidosis upon autopsy in a patient with acute respiratory distress syndrome (ARDS) of unknown cause highlights the importance of physicians taking into account this uncommon disease association for quicker diagnosis and treatment. The study, “Sarcoidosis Presenting as Acute Respiratory Distress Syndrome,” was…

Deaths attributed to sarcoidosis as the primary underlying cause increased between 1999 and 2016 in the United States, according to a recent observational study. The study, “Sarcoidosis deaths in the United States: 1999–2016,” published in the journal Respiratory Medicine, compared death rates among different regions, races, genders, and…

Two cardiologists in the Netherlands are using an artificial intelligence (AI) tool called the VMS Heart Analysis System, developed by Ventripoint Diagnostics, for the early diagnosis of pulmonary hypertension in sarcoidosis patients. With this tool, Marco Post, MD, PhD, and Marloes Huitema, MD, at the St. Antonius…

A research team at Yale School of Medicine successfully treated a person with disfiguring sarcoidosis with Xeljanz (tofacitinib) — an existing approved treatment against rheumatoid arthritis — resulting in a near-complete disappearance of skin lesions. The findings were published in the New England Journal of Medicine in an…

After the U.S. Food and Drug Administration accepted aTyr Pharma‘s investigational new drug application for ATYR1923, the company announced it will initiate a Phase 1b/2a clinical trial in patients with pulmonary sarcoidosis. The company will collaborate with the Foundation for Sarcoidosis Research (FSR) for the…

Low levels of white blood cells in the blood — a condition known as lymphopaenia — could be a useful, noninvasive biomarker for the diagnosis of ocular sarcoidosis, a study reports. The study, “Lymphopaenia as a predictor of sarcoidosis in patients with a first episode of uveitis,”…

More studies describing symptoms and disease severity in people with sarcoidosis and psoriasis are urgently needed to understand how the diseases may increase the risk of other medical conditions, a cross-sectional study says. “Examining the epidemiology of coincident psoriasis and sarcoidosis: An observational cross-sectional study,” was published in the…

Researchers have reported a new case of cutaneous sarcoidosis in a Finnish woman previously treated for Hodgkin’s lymphoma — a type of blood cancer — noting that sarcoidosis development after lymphoma may be underreported. These insights were highlighted in a correspondence titled “Cutaneous sarcoidosis after Hodgkin…

Treatment with Rituxan (rituximab) provided marked disease remission and was well-tolerated by three patients with refractory neurosarcoidosis, according to a new case report. The study, “Successful therapy with rituximab in three patients with probable neurosarcoidosis,” was published in the journal Therapeutic Advances in Neurological…