Durezol (difluprednate) is a U.S. Food and Drug Administration (FDA)-approved medication for the treatment of inflammation and pain associated with ocular surgery. Durezol was developed by Sirion Therapeutics, but the company sold its U.S. rights to Durezol to Alcon in 2010. Durezol, a corticosteroid, is also used…
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A G908R mutation in the NOD2 gene is an indicator of familial sarcoidosis, according to a French study. When present in combination with IL17RA, EPHA2, and KALRN gene variants, it influences disease progression, researchers reported. Their study, “G908R NOD2 variant in a family with sarcoidosis,” was published…
Sarcoidosis patients can be divided into women over age 40 with skin and eye lesions, and men under 40 with lung involvement, according to a large survey conducted in Japan. The study, titled “Nationwide survey on the organ-specific prevalence and its interaction with sarcoidosis in Japan,”…
A recent study shows that while lung function was unaffected, patients with fibrotic sarcoidosis report increased respiratory symptoms and decreased quality of life after short-term exposure to air pollution. This small cohort study, titled “Short-Term Particulate Air Pollution Exposure is Associated with Increased Severity of Respiratory and…
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Case Report Describes Rare Coexistence of Sarcoidosis and Tuberculosis in Patient with Severe PAH
A new case report from India describes the occurrence of both sarcoidosis and tuberculosis (TB) in a patient with severe pulmonary arterial hypertension (PAH), and highlights the importance of early treatment in these rare cases. The study, “Coexistence of Sarcoidosis and Tuberculosis Presenting with Severe…
Sarcoidosis during pregnancy is a rare event affecting only 9.6 out of 100,000 births. Sarcoidosis does not prevent pregnancy or affect fertility in women. Studies also have shown that maternal sarcoidosis is not harmful to the baby. After the birth of a child, mothers with sarcoidosis may…
The Foundation for Sarcoidosis Research recently launched a Patient Ambassador Program called “Ask the Ambassadors!” to help people with sarcoidosis clarify questions they may have about life with the condition, treatment options, and other topics. The foundation believes that the causes of sarcoidosis, and ultimately a cure, will…
Sarcoidosis is a disease that is mainly diagnosed in adults from the ages of 20-40. It is characterized by the formation of clumps of immune cells called granulomas in different tissues and organs throughout the body. Childhood sarcoidosis is extremely rare and its true prevalence is unknown. A…
From 50-70 percent of patients with sarcoidosis are estimated to experience fatigue, which can have a severe impact on their quality of life. Causes of fatigue in sarcoidosis Sarcoidosis is an inflammatory condition that causes abnormal deposits of immune cells, known as granulomas, to build up in different parts…
Levels of endocan, an indicator of inflammation, can be used as a predictive biomarker for the involvement of the cardiovascular system and the development of atherosclerosis in patients with sarcoidosis, a new study shows. The study titled, “Endocan Levels and Endothelial Dysfunction in Patients With Sarcoidosis,” was published…