Male sarcoidosis patients and those who use immunosuppressive agents — particularly Cytoxan (cyclophosphamide) — are more likely to get severe infections than women with the disease and those who don’t take such medications, a French study suggests. The study “Severe infections in sarcoidosis: Incidence, predictors and long-term outcome in a cohort of…
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A large proportion of sarcoidosis patients live with severe chronic pain despite the heavy use of painkillers, including opioids, a recent survey found. In addition, pain considerably impacts their walking ability, sleep, and enjoyment of life. Based on the survey results, researchers argue that the nerve damage that causes…
Researchers found higher numbers of two species of bacteria in the lungs of patients with sarcoidosis, and call for further studies to better understand their importance in the development of the disease. The study, “Atopobium and Fusobacterium as novel candidates for sarcoidosis-associated microbiota,” was published in…
A study found that the biggest share — 72% — of total healthcare costs among sarcoidosis patients in the U.S. is spent on the top 20% of the most costly patients. And these high-cost patients were found to have more complicated health conditions, the study said. The study, titled “…
Imaging data collected by advanced cardiac magnetic resonance (CMR) can significantly improve the diagnosis of cardiac sarcoidosis and accurately predict the risk of future life-threatening cardiac events, a study found. The study, “Complementary Role of CMR to Conventional Screening in the Diagnosis and Prognosis of Cardiac Sarcoidosis,”…
Radiotherapy may be useful for the control of sarcoidosis associated with bone involvement, according to a recent case report. “Emergency Radiotherapy for Spinal Cord Compression” was published in the journal Internal Medicine, a Japanese publication, and reports the case of a 68-year-old man complaining of right shoulder pain…
Treatment with Remicade (infliximab) in neurosarcoidosis patients is associated with favorable imaging and clinical treatment responses, new research shows. The study, “Infliximab for the treatment of CNS sarcoidosis,” was published in the journal Neurology. Neurosarcoidosis occurs in about 5% to 15% of patients with sarcoidosis…
aTyr Pharma has dosed the first person in its Phase 1 study of iMod.Fc (ATYR1923) — an investigational therapy developed for patients with interstitial lung diseases, including sarcoidosis. The study is the first to test the compound in humans and will compare the treatment to a placebo in healthy…
The Oklahoma Medical Research Foundation (OMRF) is seeking volunteers to participate in sample donations for the launch of a new Sarcoidosis Research Clinic. Volunteers needed include healthy individuals and people with a sarcoidosis diagnosis. Both African-American and European-American individuals are eligible to participate. The clinic is the first…
The bacterium Propionibacterium acnes may cause ocular sarcoidosis, as researchers have detected high levels of the pathogen in retinal granulomas of patients with the condition. These findings suggest that new therapies for the disease may include antibiotics targeting the infection. The study, “Immunohistochemical Detection of Propionibacterium acnes in the…