Higher doses of the investigational therapy efzofitimod significantly reduced relapse rates after a dose of a corticosteroid was reduced in people with pulmonary sarcoidosis, according to a new, pooled analysis of Phase 1b/2a trial data. The first-in-class immunomodulatory therapy, developed by aTyr Pharma, also significantly improved lung…

How do I know that my hip is getting better? My back is hurting more. I know that sounds like a bad joke, but it really falls into the category of “funny ’cause it’s true.” It’s not actually funny, but laughter is a great coping mechanism. Sometimes I can’t tell…

One of my wife’s friends recently invited us to a party. It happened to be our anniversary weekend and we didn’t have any plans, so we decided to make it a date. It was a great opportunity to hang out with some nice folks. After arriving, I overheard a few…

Most cardiac sarcoidosis patients respond to six months of first-line treatment with the corticosteroid prednisolone and show reduced active inflammation in the heart, according to a small study in Japan. Cardiovascular events were less common among responders relative to those who respondly poorly, further confirming first-line prednisolone’s effectiveness…

“Be who you are and say what you feel, because those who mind don’t matter, and those who matter don’t mind.” — Anonymous Every other week before I meet with my therapist, I take stock of where my head is at: what I’m thinking most about, what’s stressing me…

“Start where you are. Use what you have. Do what you can.” — tennis champion Arthur Ashe Six years ago, my life changed. That’s when I experienced my first spontaneous pneumothorax, or a sudden collapsed lung. The year before, I’d been laid off from my job. I spent that…

“Baseball is 90% mental. The other half is physical.” — New York Yankees Hall of Famer Yogi Berra It seems we’re never going to make it to a post-COVID world. It’s never going to be gone — or if it is, other variants or viruses will likely take its place.

Patterns of multiorgan involvement in African Americans with sarcoidosis differ from those of Americans of European ancestry, a study suggests. But in both groups, certain genetic mutations are associated with specific patterns of organ involvement. Collectively, its findings “support ancestry-specific differences likely resulting from distinct social, cultural, and environmental…

When I told my primary physician a few months ago that I was diagnosed with avascular necrosis (also known as AVN or osteonecrosis) and would be having a total hip replacement in early June, he offered his sympathies. I understood that inclination, but I was thrilled. I would have…

Meitheal Pharmaceuticals has entered into an agreement with Xentria to market XTMAB-16, the investigational treatment for pulmonary sarcoidosis, should it be approved in the future. Under the terms of the agreement, Meitheal gains the sole rights to sell and distribute XTMAB-16 in North America. Xentria retains the…