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Araim Pharmaceuticals recently announced that its lead candidate, Innate Repair Receptor (IRR) activator ARA 290, has been designed an orphan drug for the treatment of sarcoidosis by the U.S. Food and Drug Administration (FDA). ARA 290, a synthetic 11-amino acid peptide IRR agonist, is currently in Phase 2 clinical trials as a potential treatment…

Cardiac sarcoidosis differential diagnosis — being able to differentiate between cardiac sarcoidosis and other diseases with similar symptoms — is critical due to the progressive nature of the condition and the existence of effective treatment strategies for patients. Now, researchers at the University of Texas Health Science Center at Houston and…

Researchers from Hospital Ana Costa, in Brazil, presented a rare case of orbital sarcoidosis, affecting one eye, without involving the tear producing lacrimal gland, the most common site of sarcoidosis in the eyes. The study, “Unilateral Eyelid Edema as Initial Sign of Orbital Sarcoidosis,” published in the journal…

Sarcoidosis may have several associated diseases, including arterial hypertension, thyroid disorders, diabetes, lung diseases, and obesity – and now familial Mediterranean fever (FMF), an autoinflammatory disease, according to the study “Coexistence of sarcoidosis and Familial Mediterranean Fever,” from the  journal Reumatología Clínica. In the study, researchers…

The symptoms of sarcoidosis often mimic those of other disorders, leading to under- or over-diagnosis of the disease. An understanding of the clinical manifestations that may lead to sarcoidosis misdiagnosis is necessary for clinicians, according to a study of case reports. Sarcoidosis is characterized by the growth of small collections of inflammatory…

Researchers from Karolinska Institutet in Sweden, reported finding eight proteins in bronchoalveolar fluid (lung washing liquid) in the largest group of patients with sarcoidosis to be studied that distinguishes people with the disease from healthy people and those with asthma. The findings presented in the report “Elevated levels of…