A wearable cardioverter-defibrillator can prevent sudden death in patients with cardiac sarcoidosis, new research demonstrates. A study found the device was capable of restoring heart rhythm in all patients who experienced abnormal and potentially life-threatening heartbeats. Results were reported in the study,…
Search results for:
Sarcoidosis is a rare inflammatory disease characterized by the formation of immune cell clumps called granulomas. These granulomas can form in different parts of the body, and may interfere with the normal function of tissues and organs. When they form in and around the nervous system, the condition is…
People with sarcoidosis have a higher degree of physical inactivity compared with healthy individuals, a pilot study led by researchers from the King’s College London shows. Physical activity monitors, such as the accelerometer device ActivPal, can provide a unique perspective on the impact of sarcoidosis on patients’…
A woman who underwent a heart transplant for cardiac sarcoidosis later showed signs of sarcoidosis in the brain, a condition known as neurosarcoidosis, highlighting the need for better protocols to monitor and treat sarcoidosis patients after a transplant, scientists report. Immunosuppressive treatments helped to ease the woman’s neurological…
The investigational therapy ATYR1923 for pulmonary sarcoidosis may help decrease lung inflammation by halting the infiltration of immune cells called neutrophils into the lungs, according to a preclinical study in mice. Suzanne Paz, PhD, from the therapy’s developer aTyr Pharma, presented the findings in a poster, titled “…
Only about half of sarcoidosis patients showing signs of muscle disease, or myopathy, have the small clumps of immune cells in their muscles that characterize sarcoidosis, a study showed. When these clumps, called granulomas, weren’t present with muscle symptoms, myopathy was most often linked to inclusion body myositis (IBM),…
Despite advances in testing, fewer than one of every six people evaluated for suspected neurosarcoidosis — sarcoidosis affecting the nervous system — received a definite diagnosis of the inflammatory disorder, according to a 30-year study in Sweden. A confirmed neurosarcoidosis diagnosis in those cases was made only following a…
Greater exposure to the experimental treatment efzofitimod led to a more pronounced improvement in lung function for people with pulmonary sarcoidosis in a Phase 1/2 clinical trial, according to a new analysis. Scientists at aTyr Pharma, the company developing the first-in-class immunomodulatory therapy, presented their findings at…
Swelling of a specific vein in the brain may be a sign of neurosarcoidosis, a form of sarcoidosis that affects the nervous system, a new study suggests. “Incorporating this in the current diagnostic criteria may result in timely intervention, and we encourage radiologists to look for this marker in patients…
Although neurological symptoms are rare in people with sarcoidosis, physicians should consider neurosarcoidosis in cases of myelitis and hydrocephalus, as prompt steroid treatment can improve patient outcomes. The recommendation comes from researchers at the Jersey Shore University Medical Center in a recent case study, “Hydrocephalus…