I was diagnosed with sarcoidosis not long after my mother passed away in 2003, and it was totally by accident. I was having a conversation with a pulmonologist about participating in a sleep study. During the meeting, he talked about breathing issues and other conditions related to sleep apnea,…
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The investigational therapy ATYR1923 for pulmonary sarcoidosis may help decrease lung inflammation by halting the infiltration of immune cells called neutrophils into the lungs, according to a preclinical study in mice. Suzanne Paz, PhD, from the therapy’s developer aTyr Pharma, presented the findings in a poster, titled “…
Middle-aged adults with impaired lung function, such as people with sarcoidosis, are at higher risk of dementia and mild cognitive impairment, according to a long-term follow-up study. The study, “Impaired Lung Function, Lung Disease and Risk of Incident Dementia” was published in the American Journal of…
Better quality of life and greater functionality are the most important treatment goals for people with sarcoidosis, according to a large-scale survey of patient perspectives. Survey results are expected to be included in European Respiratory Society (ERS) guidelines to be released this year. They were reported in “…
Highly sensitive magnetic resonance imaging (MRI) of the spinal cord shows that spine involvement is prevalent in sarcoidosis patients, mostly affecting the cervical region, a detailed re-analysis of imaging data reports. The study, “Imaging findings in spinal sarcoidosis: a report of 18 cases and review…
Leukeran (chlorambucil) is a chemotherapy agent used to treat certain forms of leukemia. It is used selectively to treat sarcoidosis patients who do not respond to corticosteroids. How Leukeran works Sarcoidosis is a chronic disease in which immune cells surround threats, but instead of destroying the threat…
Remicade (infliximab) is a monoclonal antibody therapy developed by Janssen and approved by the U.S. Food and Drug Administration (FDA) to treat several inflammatory diseases including rheumatoid arthritis and Crohn’s disease. The treatment also can be used for sarcoidosis when patients do not respond to…
Rituximab is a medication that targets immune system cells called B-cells, and can be used to treat sarcoidosis. Rituximab, marketed as Rituxan and manufactured by Genentech, has been approved by the U.S. Food and Drug Administration (FDA) to treat rheumatoid arthritis; blood cancers…
Pentoxifylline is a treatment that has been approved by the U.S. Food and Drug Administration to improve blood flow. It can also be used to treat sarcoidosis. How pentoxifylline works In addition to improving blood flow, pentoxifylline inhibits the synthesis of a pro-inflammatory, or immune-activating factor, called…
Sarcoidosis is characterized by clumps of immune cells called granulomas that build up in one or more parts of the body. These can cause chronic inflammation and prevent the normal function of organs. There is no cure for sarcoidosis, but there are various therapies that can help manage the symptoms of…