News

A new study from researchers in Turkey suggests that a ratio taking into account the amount of angiotensin-converting enzyme (ACE) and of lymphocytes, a type of white blood cell — a ratio elevated in patients with recurrent disease after stopping treatment — is a potential biomarker for people with…

Most people with inflammatory conditions reported overall satisfaction, convenience, and confidence when self-administering Acthar Gel (repository corticotropin injection) through a single-dose, prefilled injector called SelfJect. That’s according to a survey-based study sponsored by the therapy’s developer, Mallinckrodt. The study involved 54 patients living in the U.S., eight of…

A Partner Grant from the Foundation for Sarcoidosis Research (FSR) and the American Thoracic Society (ATS) will support a research project focused on possible connections between air pollution and outcomes of people with sarcoidosis. The grant, totaling $100,000 over two years, was awarded to Mark Mallozzi, MD,…

The first participants in a Phase 2 clinical trial testing brepocitinib, Roivant’s experimental oral treatment, in adults with cutaneous sarcoidosis have been dosed, and top-line results are expected in the second half of 2026. The company had this year announced plans to launch this proof-of-concept trial, called BEACON…

Methotrexate appears to take longer to start acting, but is no less effective than the corticosteroid prednisone as a first-line treatment for pulmonary sarcoidosis, according to the early findings of an ongoing Phase 4 clinical trial. The researchers noted that, while methotrexate treatment is associated with a similar number…

Many people with moderate or severe pulmonary sarcoidosis — the target market for the investigational therapy efzofitimod — are highly burdened by the disease and are dependent on corticosteroids that can have serious side effects, according to real-world analyses. “New real-world evidence underscores the growing burden of patients…

The prevalence of sarcoidosis, or the proportion of people with the condition in a population, has roughly doubled over the past 30 years in a region in Norway, a large population-based study shows, and the incidence of sarcoidosis, that is, the number of new cases within a given time,…

April has officially been recognized as Sarcoidosis Awareness Month in the U.S., marking a significant milestone for the community and its advocates, according to the Foundation for Sarcoidosis Research (FSR) — which also celebrates its 25th anniversary this year. The recognition by the U.S. Congress was spearheaded by Danny…

More than two dozen mutations that seem to increase the risk of developing sarcoidosis were identified in a new study. Notably, 17 of the 28 mutations hadn’t been linked to the inflammatory disease. Higher genetically predicted body mass index (BMI) and higher levels of several proteins involved in inflammation…

The findings of a new preclinical study in pulmonary sarcoidosis are lending support to the therapeutic potential of efzofitimod, a treatment candidate from Atyr Pharma now being tested in a Phase 3 clinical trial. The researchers found that a protein called HARS-WHEP — whose activity is mimicked by…