Showing 970 results for "sarcoidosis"

No benefit to methotrexate over prednisolone in poor responders

Most cardiac sarcoidosis patients respond to six months of first-line treatment with the corticosteroid prednisolone and show reduced active inflammation in the heart, according to a small study in Japan. Cardiovascular events were less common among responders relative to those who respondly poorly, further confirming first-line prednisolone’s effectiveness…

Patterns of organ involvement can differ by racial ancestry

Patterns of multiorgan involvement in African Americans with sarcoidosis differ from those of Americans of European ancestry, a study suggests. But in both groups, certain genetic mutations are associated with specific patterns of organ involvement. Collectively, its findings “support ancestry-specific differences likely resulting from distinct social, cultural, and environmental…

How a hip replacement brought me happiness and hope

When I told my primary physician a few months ago that I was diagnosed with avascular necrosis (also known as AVN or osteonecrosis) and would be having a total hip replacement in early June, he offered his sympathies. I understood that inclination, but I was thrilled. I would have…

Meitheal, Xentria make pact to market XTMAB-16

Meitheal Pharmaceuticals has entered into an agreement with Xentria to market XTMAB-16, the investigational treatment for pulmonary sarcoidosis, should it be approved in the future. Under the terms of the agreement, Meitheal gains the sole rights to sell and distribute XTMAB-16 in North America. Xentria retains the…

More efzofitimod exposure linked to better lung function in trial

Greater exposure to the experimental treatment efzofitimod led to a more pronounced improvement in lung function for people with pulmonary sarcoidosis in a Phase 1/2 clinical trial, according to a new analysis. Scientists at aTyr Pharma, the company developing the first-in-class immunomodulatory therapy, presented their findings at…