More than two dozen mutations that seem to increase the risk of developing sarcoidosis were identified in a new study. Notably, 17 of the 28 mutations hadn’t been linked to the inflammatory disease. Higher genetically predicted body mass index (BMI) and higher levels of several proteins involved in inflammation…

Elevated blood levels of fatty molecules, or lipids — specifically triglycerides and low-density lipoprotein cholesterol (LDL-c), also known as bad cholesterol — may be linked with an increased risk of developing sarcoidosis, while certain lipid-lowering medications may help reduce the risk. That’s according to a study that looked at…

People with sarcoidosis are significantly more likely to develop venous thromboembolism (VTE), which occurs when a blood clot forms in a vein, over 10 years than the general population, a nationwide study in Denmark suggests. And while there are substantial differences in clinical characteristics between those who develop VTE…

Menopausal hormone therapy (MHT) is linked to a 25% higher risk of developing sarcoidosis, according to a recent study in Sweden. The therapy consists of administering sex hormones, either estrogen alone or an estrogen and progesterone combination, to treat common menopausal symptoms such as “hot flashes.” The highest risk…

A noninvasive heart imaging scan may help identify cardiac sarcoidosis patients at risk of worse clinical outcomes, according to a study. A value of 42% or lower in left ventricular ejection fraction, or LVEF, a measure of how much blood is being pumped out of the heart’s left ventricle…

The risks of death and rejection after heart transplant for people with advanced cardiac sarcoidosis were similar to those of patients who had transplants for other types of heart disease, according to an analysis of a transplant recipient registry. These findings suggest that a heart transplant is a safe…

People with autoimmune diseases such as sarcoidosis are not at higher risk of worse outcomes following lung or heart-lung transplants compared with people without such diseases, a new single-center study shows. The findings that autoimmune patients fare as well as others following such transplants refute the long standard approach…

Although uncommon, some people with cancer will develop granulomas, the clumps of immune cells that are a hallmark of sarcoidosis — and those who do are more likely to have better survival outcomes, a new study reports. The study, “Presence of concurrent sarcoid-like granulomas indicates better…

Exposure to inhaled silica dust appears to increase the risk of sarcoidosis among men 20 to 65 years old, according to a recent study from Sweden. Men 35 and younger, and older men with more than six years of regular exposure to the dust saw the highest risk.

People with sarcoidosis who have impaired lung function seem to be at greater risk for severe COVID-19 disease, a new study suggests. The study, “Moderate or Severe Impairment in Pulmonary Function is Associated with Mortality in Sarcoidosis Patients Infected with SARS‑CoV‑2,” was published in the journal …