News

Nonsteroidal immunosuppressants may be a treatment option for people with cardiac sarcoidosis who don’t respond well to corticosteroids or have side effects from using them, a Japanese study suggests. While nonsteroidal immunosuppressants reduced the need for corticosteroids and how active sarcoidosis lesions were for some patients, more research is…

Two early-career scientists each were awarded $150,000 Sarcoidosis Research Fellowship grants from the Foundation for Sarcoidosis Research (FSR) to support projects that aim to investigate the causes of sarcoidosis and improve patient outcomes. The fellowships were awarded to Greer Waldrop, MD, PhD, at the University of California,…

High blood calcium levels, or hypercalcemia, may in rare cases be a symptom of sarcoidosis, according to a case report from Morocco. Steroid medications helped ease the symptom for a man with severe hypercalcemia as a main complication of sarcoidosis of the lungs, or pulmonary sarcoidosis, according to…

A 30-year-old man with renal cell carcinoma — a type of kidney cancer — developed sarcoid-like reactions in his spleen, liver, and lungs, which went away after the tumor’s removal, suggesting that such reactions arose from an unusual immune response against the tumor. The man’s case was described in a…

Enrollment in aTyr Pharma’s pivotal Phase 3 EFZO-FIT clinical trial, testing the effectiveness and safety of efzofitimod in people with pulmonary sarcoidosis, is now complete. The study exceeded its target number of participants, recruiting 268 patients in 85 centers across the U.S., Europe, Japan, and Brazil. Top-line data are expected…

Being Black or having restrictive lung disease, where it’s hard to take in enough air in a breath, were factors that predicted faster lung function declines in people with pulmonary sarcoidosis in a recent U.S. study. “This study can inform future prospective studies to further explore pulmonary function phenotypes…

A woman who underwent a heart transplant for cardiac sarcoidosis later showed signs of sarcoidosis in the brain, a condition known as neurosarcoidosis, highlighting the need for better protocols to monitor and treat sarcoidosis patients after a transplant, scientists report. Immunosuppressive treatments helped to ease the woman’s neurological…

A new modeling approach that incorporates standard tests and clinical signs can identify people who have sarcoidosis-associated uveitis (SAU), or inflammation of the eye, a new study shows. Based on this analysis, data showed a combination of eye tests could distinguish SAU from non-SAU patients with a high degree…

Microblading, a cosmetic technique that employs fine needles to deposit pigment to mimic the appearance of hairs, may be among triggers for sarcoidosis, according to a study. “When esthetic procedures become increasingly popular, patients with chronic lesions at the injection site of the foreign material, especially macular, papular, or…

People with sarcoidosis in the U.S. are more likely than those in the general population to have certain co-occurring autoimmune disorders, including lupus and multiple sclerosis (MS). That’s according to “Autoimmune comorbidities associated with sarcoidosis: a case-control study in the All of Us research program,” which…