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Elevated levels of calcium in blood and urine can be associated with the development of bone marrow sarcoidosis, according to a report published in the journal Biomarker Research. The study, “Hypercalcemia Associated With Isolated Bone Marrow Sarcoidosis In A Patient With Underlying Monoclonal Gammopathy Of Undetermined Significance: Case…

Genome-wide analysis of lung samples from pulmonary sarcoidosis patients and a healthy control group identified a set of genes whose expression is altered only in disease samples. These results may lead to new biomarkers for pulmonary sarcoidosis. The study, “Bioinformatics analysis of gene expression profile data to screen key…

Sarcoidosis can present several distinct clinical manifestations, and some of these can mimic other diseases. Therefore, it is essential for clinicians to have as much complete and detailed information as possible to allow for an accurate diagnosis. Skin manifestations can be the first symptom of sarcoidosis. But sarcoidosis and chronic cutaneous lupus…

Sarcoidosis should be considered as a differential diagnosis in case of nail lesions, according to a study published in the journal Skin Appendage Disorders, where researchers from São Paulo in Brazil report the case of two patients. This would allow an early diagnosis of systemic sarcoidosis.

Cryptococcal meningitis, a rare but life-threatening complication of sarcoidosis, is often misdiagnosed as neurosarcoidosis, delaying proper treatment and reducing a patient’s chances of complete recovery, researchers report. Investigators behind the study, “Cryptococcal meningitis complicating sarcoidosis,” published in the journal Medicine, suggest that physicians test for CSF…

A new study suggests that sarcoidosis patients have different expression levels of certain RNA-binding proteins (RBPs) compared to healthy individuals, and that this difference is associated with the development of the disease. The study, “Expression Profile of Six RNA-Binding Proteins in Pulmonary Sarcoidosis,” was published in the journal…

Patients with sarcoidosis may develop a condition known as autoimmune hemolytic anemia, in which the red blood cells are prematurely destroyed by the immune system. Although this is not well documented, researchers at Warwick Hospital in England have reported the case of a patient who exhibited both illnesses. Their study,…

There is a difference in the composition of microorganisms in the respiratory tract of people with sarcoidosis and that of healthy individuals according to a study conducted by Polish scientists. The authors of the study suggest that this may be a factor contributing to an increased colonization of the airways by opportunistic pathogenic bacteria.

Poor cardiac outcomes in patients with cardiac sarcoidosis may be predicted through the presence of cardiac fibrosis assessed by heart magnetic resonance imaging (MRI), according to a recent Japanese study. The study, “Risk stratification for major adverse cardiac events and ventricular tachyarrhythmias by cardiac MRI in patients with…

The results of a clinical study conducted over 20 years in a group of patients seen and treated at three large teaching hospitals in London shows that patients with sarcoidosis who experience an inflammatory optic neuropathy, or damage to the optic nerve due to inflammation, respond to treatment with corticosteroids.