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Women tend to develop sarcoidosis when they are older and tend to have more uveitis, or eye inflammation and cutaneous involvement compared to men, according to a retrospective study conducted on people diagnosed with the disease between 1976 and 2013.

Genes that have been linked to the likelihood of developing sarcoidosis may not necessarily be associated with disease course, according to a study conducted in Portugal, which also points to other genes that may help to predict a patient’s outcome. The study, “Associations Between Sarcoidosis Clinical Course And ANXA11 Rs1049550 C/T, BTNL2 Rs2076530 G/A,…

Sarcoidosis patients who are prescribed vitamin D supplements show increased risk for hypercalcemia (high calcium levels in the blood), highlighting the need for more appropriate screening when prescribing vitamin D in these patients. The study, “Vitamin D Supplementation: Not So Simple in Sarcoidosis,” was published in The American…

Exposure to mold and bacteria could be a potential trigger of lung sarcoidosis, according to a study revealing that immune cells from the blood of sarcoidosis patients are more sensitive to such agents. The study, “Fungal cell wall agents and bacterial lipopolysaccharide in organic dust as possible risk…

Elevated levels of calcium in blood and urine can be associated with the development of bone marrow sarcoidosis, according to a report published in the journal Biomarker Research. The study, “Hypercalcemia Associated With Isolated Bone Marrow Sarcoidosis In A Patient With Underlying Monoclonal Gammopathy Of Undetermined Significance: Case…

Genome-wide analysis of lung samples from pulmonary sarcoidosis patients and a healthy control group identified a set of genes whose expression is altered only in disease samples. These results may lead to new biomarkers for pulmonary sarcoidosis. The study, “Bioinformatics analysis of gene expression profile data to screen key…

Sarcoidosis can present several distinct clinical manifestations, and some of these can mimic other diseases. Therefore, it is essential for clinicians to have as much complete and detailed information as possible to allow for an accurate diagnosis. Skin manifestations can be the first symptom of sarcoidosis. But sarcoidosis and chronic cutaneous lupus…

Sarcoidosis should be considered as a differential diagnosis in case of nail lesions, according to a study published in the journal Skin Appendage Disorders, where researchers from São Paulo in Brazil report the case of two patients. This would allow an early diagnosis of systemic sarcoidosis.

Cryptococcal meningitis, a rare but life-threatening complication of sarcoidosis, is often misdiagnosed as neurosarcoidosis, delaying proper treatment and reducing a patient’s chances of complete recovery, researchers report. Investigators behind the study, “Cryptococcal meningitis complicating sarcoidosis,” published in the journal Medicine, suggest that physicians test for CSF…

A new study suggests that sarcoidosis patients have different expression levels of certain RNA-binding proteins (RBPs) compared to healthy individuals, and that this difference is associated with the development of the disease. The study, “Expression Profile of Six RNA-Binding Proteins in Pulmonary Sarcoidosis,” was published in the journal…