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Cardiac Sarcoidosis May Be Diagnosed by Analyzing Select Immune Cells in Heart Tissue

Cardiac sarcoidosis might be accurately diagnosed by measuring the ratio of immune cells, specifically macrophages and dendritic cells, in tissue samples from patients, researchers reported. The study, “Myocardial Immunocompetent Cells and Macrophage Phenotypes as Histopathological Surrogates for Diagnosis of Cardiac Sarcoidosis in Japanese,” was published in the Journal…

Corticosteroid Therapy Started Early Seen to Notably Benefit Cardiac Sarcoidosis Patients

The sooner patients with cardiac sarcoidosis start corticosteroid therapy, the better are their chances of improvement and positive outcomes,a new study published in the International Journal of Cardiology reports. The study, “Impact Of Early Initiation Of Corticosteroid Therapy On Cardiac Function And Rhythm In Patients With Cardiac Sarcoidosis,” was conducted…

Cardiac Sarcoidosis Diagnosed in Heart Patient Only After Lung Biopsy

In rare cases, cardiac sarcoidosis (CS) can lead to heart failure — although this risk is not often considered by physicians unaccustomed to seeing it. Sarcoidosis patients with cardiac involvement, however, have an overall worse prognosis than those without it, according to a study published in  the journal Heart Failure Reviews. Drawing on a case…

Sarcoidosis Found in Lymph Nodes of Breast Cancer Patient in Case Study

A case study of a woman, with both breast cancer and sarcoidosis in her breast lymph nodes, highlights the difficulties in distinguishing between these two conditions. The report, “Sarcoidosis imitating breast cancer metastasis: a case report and literature review,” published in the journal Cancer Biology & Medicine, also again calls attention to an apparent…

Receptor That Recognizes Infections May Trigger Pulmonary Sarcoidosis

Researchers recently linked pulmonary sarcoidosis to a receptor activated during certain infections that may contribute to disease development via the release of an inflammatory factor in immune cells. The study, “Functional Toll-Like Receptor 9 Expression and CXCR3 Ligand Release in Pulmonary Sarcoidosis,” was published in the American Journal…

Researchers Report Case of Sarcoidosis, Pulmonary Hypertension Patient

Sarcoidosis patients may develop pulmonary hypertension that leads to severe heart complications, according to a study published in the journal Case Reports in Cardiology. In the study, “Multifactorial Etiology Pulmonary Hypertension In A Patient With Sarcoidosis,” researchers described a case of pulmonary sarcoidosis, heart failure, and pulmonary hypertension (PH) that…