A potent signaling molecule called interleukin-33, or IL-33, can restore the balance and function of regulatory immune T-cells in mice with pulmonary sarcoidosis, a study showed. The finding suggests that IL-33 may become an important target in preventing the immune-mediated inflammatory processes of pulmonary sarcoidosis. The study, “…
The number of patients diagnosed with sarcoidosis increased in the last decade in Korea, and women in their 50s and 60s were found to be at higher risk, a Korean study shows. The findings were reported in the Respiratory Research journal in the study “Prevalence and incidence of…
Measuring the serum levels of the proteins ACE, YKL-40, CRP, and sIL-2R may enable clinicians to monitor disease activity in sarcoidosis patients, according to researchers from Turkey. Their study, “YKL-40, Soluble IL-2 Receptor, Angiotensin Converting Enzyme and C-Reactive Protein: Comparison of Markers of Sarcoidosis Activity,” was published in…
Excessive daytime sleepiness is about twice as frequent in patients with sarcoidosis than in the general population, according to researchers from Germany. The study, “Daytime sleepiness in patients diagnosed with sarcoidosis compared with the general population,” conducted by a team from the University of Leipzig and the Magdeburg-Stendal University…
Older patients tend to show fewer symptoms and abnormal lab results typically associated with ocular sarcoidosis than younger patients, making diagnosis more difficult, a study has found. These findings highlight the need for more studies to explore and find other types of symptoms that could assist with disease diagnosis…
Elderly-onset sarcoidosis patients have different disease and diagnostic features compared to younger-onset patients, researchers from Turkey have found. Sarcoidosis is often diagnosed in young patients between the ages of 25 and 40. But 30% of the cases are usually diagnosed in older individuals. So there are two forms of the…
The levels of two blood-circulating microRNAs, called microRNA-126 and microRNA-223, may work as new biomarkers for cardiac sarcoidosis, according to researchers. Their small study, “Serum microRNA-126 and -223 as new-generation biomarkers for sarcoidosis in patients with heart failure,” was published in the Journal of Cardiology. Cardiac…
The occurrence of sarcoidosis and sarcoma — a rare type of cancer — at the same time or one after the other may be more common than previously thought, according to a small study. These results highlight a potential association between these two distinct diseases, which could change…
Cryptogenic organizing pneumonia, a rare lung disease, can develop in patients with sarcoidosis, according to a new case study from India. The report, “Cryptogenic Organizing Pneumonia with Sarcoidosis Overlap: An Atypical Case Study,” was published in the journal Case Reports in Medicine. Cryptogenic organizing pneumonia, also known…
Neurosarcoidosis — a rare form of sarcoidosis affecting the central nervous system — can be misdiagnosed as meningitis because of similarities in neurological symptoms, a case study from Mexico reports. Meningitis is an inflammation of the membranes, called meninges, that surround and protect the brain and spinal cord.
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