Enrollment in aTyr Pharma’s pivotal Phase 3 EFZO-FIT clinical trial, testing the effectiveness and safety of efzofitimod in people with pulmonary sarcoidosis, is now complete. The study exceeded its target number of participants, recruiting 268 patients in 85 centers across the U.S., Europe, Japan, and Brazil. Top-line data are expected…
Being Black or having restrictive lung disease, where it’s hard to take in enough air in a breath, were factors that predicted faster lung function declines in people with pulmonary sarcoidosis in a recent U.S. study. “This study can inform future prospective studies to further explore pulmonary function phenotypes…
A woman who underwent a heart transplant for cardiac sarcoidosis later showed signs of sarcoidosis in the brain, a condition known as neurosarcoidosis, highlighting the need for better protocols to monitor and treat sarcoidosis patients after a transplant, scientists report. Immunosuppressive treatments helped to ease the woman’s neurological…
A new modeling approach that incorporates standard tests and clinical signs can identify people who have sarcoidosis-associated uveitis (SAU), or inflammation of the eye, a new study shows. Based on this analysis, data showed a combination of eye tests could distinguish SAU from non-SAU patients with a high degree…
Microblading, a cosmetic technique that employs fine needles to deposit pigment to mimic the appearance of hairs, may be among triggers for sarcoidosis, according to a study. “When esthetic procedures become increasingly popular, patients with chronic lesions at the injection site of the foreign material, especially macular, papular, or…
People with sarcoidosis in the U.S. are more likely than those in the general population to have certain co-occurring autoimmune disorders, including lupus and multiple sclerosis (MS). That’s according to “Autoimmune comorbidities associated with sarcoidosis: a case-control study in the All of Us research program,” which…
A 79-year-old woman was diagnosed with spinal sarcoidosis based on the analysis of skin lesions from her scalp, according to a case study from Japan. Although a spinal MRI revealed the presence of spinal cord lesions, their cause was unknown. The presence of skin granulomas, observed in a scalp…
A 37-year-old woman in Japan developed a granuloma — the clumps of cells that characterize sarcoidosis — in her thyroid gland that spontaneously regressed without steroid treatment, a case study reports. The woman also showed lesions in the skin and salivary gland, suggesting “thyroid sarcoidosis should be considered in…
The Foundation for Sarcoidosis Research (FSR) has launched the Coalition for Clinical Trial Equity, aimed at increasing the representation of Black and African American sarcoidosis patients in trials testing potential treatments. Despite Black Americans being 2.5 times more likely to have sarcoidosis than white Americans, these patients…
A sarcoidosis patient and ardent supporter of the Foundation for Sarcoidosis Research (FSR) was dubbed a “warrior” by the nonprofit for competing in the Ironman 70.3 Chattanooga triathlon, in Tennessee, to raise awareness of the rare condition as well as funds to fight it. The competition, held…
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